Women ALIVE Ministries

Home » Archive by category 'Activity'

Valve says Steam users should watch out for fraudulent CC activity

February 18th, 2012 Posted in Activity Tags:

A statement has just been issued out to all Steam users by Valve president, Gabe Newell which gives an update to last year#39;s event of intrusion where the Steam forums had been hacked and a backup file had likely been obtained which held sensitive Steam purchase information from 2004 through 2008.

When Valve admitted to the the hacking attempt in November of last year it did acknowledge that some user data including encrypted credit card information and hashed passwords had been stolen. While Valve said it did not find any evidence that the encrypted data had been hacked, advice was given that all users should still change their Steam passwords.

Gabe#39;s most recent announcement goes into a little more detail on what type of user information had been gotten a hold of.

Recently we learned that it is probable that the intruders obtained a copy of a backup file with information about Steam transactions between 2004 and 2008. Thi backup file contained user names, email addresses, encrypted billing addresses and encrypted credit card information. It did not include Steam passwords.

Gabe then went on to say that there continues to be no evidence that the encrypted credit card info or billing addresses were compromised, but irrespective of this it would be advisable as a cautionary measure to more closely watch your credit card activity and statements for a while.

Source: Valve Software

Comparable Clinical Activity for Low-, High-Dose Clofarabine

February 8th, 2012 Posted in Activity Tags:

Low and high doses of clofarabine have comparable clinical activity for the treatment of patients with higher-risk myelodysplastic syndrome, according to a study published in the Feb. 1 issue of Cancer.

FRIDAY, Jan. 27 (HealthDay News) — Low and high doses of clofarabine have comparable clinical activity for the treatment of patients with higher-risk myelodysplastic syndrome (MDS), according to a study published in the Feb. 1 issue of Cancer.

Stefan Faderl, MD, of the University of Texas MD Anderson Cancer Center in Houston, and colleagues conducted a randomized study to evaluate the activity and safety of two doses (15 versus 30 mg/m#178; daily for five days) of intravenous clofarabine in patients with higher-risk MDS. A cohort of 58 participants (median age, 68 years), including 15 patients (28 percent) with secondary MDS and 35 patients (60 percent) who had previously received DNA methyltransferase (DNMT) inhibitors, were adaptively randomized between the two dose groups.

The researchers found that the overall response rate (ORR) was 36 percent, including 26 percent of patients with complete remission (CR). The ORR was 41 percent at 15 mg/m#178; and 29 percent at 30 mg/m#178;. Patients who had failed DNMT inhibitors had lower response rates (ORR, 17 percent; CR rate, 14 percent). The eight-week mortality rate was 19 percent, with a median survival of 7.4, 13.4, and 21.7 months for all patients, responders, and complete responders, respectively. For patients randomized to 30 mg/m#178; of clofarabine, some of the adverse events, including hepatic and renal, were more severe (grade #62;2). Frequent complications included myelosuppression and infectious complications.

Both the lower and higher doses of clofarabine have comparable clinical activity, but the lower dose appeared less toxic, the authors write.

Several authors disclosed financial ties to Genzyme, which manufactures clofarabine.

Abstract

Full Text (subscription or payment may be required)

Copyright #169; 2012 HealthDay. All rights reserved.

Redistricting Roundup: Flurry of activity moves total completed maps beyond …

February 7th, 2012 Posted in Activity Tags:

As the filing deadlines for the 2012 elections get closer and closer, the redistricting process is becoming more and more frenetic across the country.

In the last two weeks, redistricting maps have been approved, thrown out by court, and introduced at a rapid rate across the country. The most intensive and controversial events have occurred in Florida, Missouri, New York, Pennsylvania and Texas.

  • Florida: The Florida State Senate has succeed in getting largely bi-partisan approval for its State Senate and US House redistricting plans. The plans passed on January 17 by a 34-6 margin. Opponents argue that the maps gained support by protecting incumbents and, thus, violate the new redistricting ammendments. However, redistricting committee chair and incoming Senate President Don Gaetz (R) defended the plans as the product of bi-partisan cooperation. Gaetz also argued that opponents plans would have weakened minority influence districts. The map is expected to favor Republicansthe GOP could theoretically hold 21/27 seats after the 2012 elections. A legal challenge is expected. However, some Republican districts were softened in order to accomodate the states demographic changes. As predicted, Allen West will be among those weakened. The plans now proceed to the House, where a committee vote is expected today and a floor vote is expected next week. These votes will also address House redistricting.
An interactive version of the congressional map can be found here.
  • Missouri: On January 17, the Missouri Supreme Court overturned the states Senate redistricting maps. The court found that the Senate plan unconstitutionally divided counties. The court also addressed two lawsuits concerning Missouris new congressional districts, ordering a lower court to review the maps for compactness the lower court had initially rejected the suit without considering the question. After these successes for redistricting opponents, a lawsuit was filed against the new state House plans with the Supreme Court. The court declined to hear the case and directed plaintiffs to filed the case in state circuit court. A new 10-member redistricting committee, composed of residents, will be appointed by the Governor to redraw the Senate maps. It is unclear if the revision process will be completed in time for the February 28 candidate filing deadline.
  • New York: After a number of delays, the Legislative Task Force on Demographic Research and Reapportionment (LATFOR) released proposed Senate and Assembly maps yesterday. Gov. Cuomo has long stated he would veto any lines not drawn by an independent process, but on Thursday, prior to the release of the maps, he was unclear about his course of action after the plans were released, saying he wants to see how the process plays out. After the lines were unveiled, however, a spokesman for the governor said that at first glance the districts were unacceptable and likely to be vetoed. The Senate plan includes the addition of a 63rd seat in a Republican dominated area upstate which would result in the division of Albany, a Democratic stronghold, for the first time. Additionally, the map merges four Senate districts based in Queens into two, all four of which are represented by Democrats, including Michael Gianaris, Chair of the Democratic Senate Campaign Committee. The Assemblys plan would create three Asian-majority districts and merge two upstate Republican districts into one. LATFOR will be holding nine public hearings on the plans beginning Monday and going through February 16.
  • Pennsylvania: After hearing arguments on January 23, the state Supreme Court threw out the new legislative maps just two days later by a vote of 4-3. Calling the redistricting approach contrary to law, the court ruled current district lines would stay in place until the Legislative Reapportionment Commission could devise a plan that was legal. With the signature filing deadline for state legislative candidates quickly approaching on February 14, the 2012 elections could take place in districts that were drawn in 2001. The court did not immediately specify its problems with the maps it is expected to render its full opinion soon. Democrats had argued that the new map unnecessarily split counties and municipalities.
  • Texas: The US Supreme Court ruled last Friday that the interim maps that had been put in place by a San Antonio federal court could not stand, sending the maps back to the lower court for redrawing. The Supreme Court said that redistricting is primarily a legislative responsibility and that the San Antonio court didnt give enough credence to the maps drawn by the Texas legislature. The ruling ordered the San Antonio court to use the legislative maps as a starting point for redrawing the boundaries. Texas officials saw this as a big win, although the ruling means 2012 election dates are again in jeopardy. Meanwhile, a three-judge federal panel in DC court continued hearings this week on whether the states legislatively-drawn maps violate the Voting Rights Act. Testimony wrapped up yesterday and closing arguments are scheduled for Tuesday. Back in Texas the San Antonio court is holding a status conference today regarding their plans moving forward for drawing new maps and accommodating the election schedule.

Heres the rest of the news from across the country.

State news

Alaska

Approximately a week after after it got underway, the trial for the remaining Alaska redistricting lawsuit drew to a close on January 17. A final decision in the case is expected to be issued by the Fairbanks Superior court by February 6. However, observers believe that the case will ultimately be decided by the Alaska Supreme Court.

Arkansas

State senator Jack Crumbly (D) and a group of residents from eastern Arkansas sued the three-member Board of Apportionment on Monday. The suit was filed in federal court. The lawsuit alleges that the new boundaries dilute the black vote in Crumblys district, as the number of voting-age blacks was lowered from 58 percent to 53 percent. The maps were defended by Board of Apportionment members Governor Mike Beebe (D) and Attorney General Dustin McDaniel (D). Crumbly is slated to face fellow Democrat Keith Ingram in the May primary.

Arizona

The final congressional and state legislative maps were approved and sent to the Department of Justice on January 17, 2012. The final vote was 3-2, with chairwoman Colleen Mathis voting in the affirmative alongside the two Democratic chairpersons. The vote was essentially a formality, as maps had been tentatively approved weeks earlier.

US seasonal flu activity picks up

February 7th, 2012 Posted in Activity Tags:

ATLANTA, Jan. 28 (UPI) — Seasonal flu activity appears to be picking up in the United States but it is still relatively low nationwide, federal health officials said.

Officials at the Centers for Disease Control and Prevention said the percentage of respiratory specimens that were positive for seasonal flu inched higher to 4.9 percent for the week of Jan. 21 from 4.3 percent reported the week before, while doctor visits for flu-like illness are below national and regional baselines.

The H3N2 virus has dominated national flu activity so far this season. Colorado, Kentucky, Missouri and Virginia reported regional flu activity — but no state has reported widespread flu activity.

CDC Region 5: Illinois, Indiana, Missouri, Ohio and Wisconsin reported the highest percent — 14 percent — of respiratory specimens that tested positive for flu.

However, CDC officials said for the past three weeks the 2009 H1N1 virus dominated CDCs Region 6 that includes Arkansas, Louisiana, New Mexico, Oklahoma and Texas, the Center for Infectious Disease Research and Policy at the University of Minnesota reported. However, these states are seeing little overall flu activity.

Federal health officials said they expect the levels of seasonal flu to increase over the coming weeks and continuing until the end of April.

New Fluorescent Dyes Highlight Neuronal Activity

February 5th, 2012 Posted in Activity Tags:

Researchers at the University of California, San Diego School of Medicine have created a new generation of fast-acting fluorescent dyes that optically highlight electrical activity in neuronal membranes. The work is published online in Early Edition of the Proceedings of the National Academy of Sciences.

The ability to visualize these small, fast-changing voltage differences between the interior and exterior of neurons – known as transmembrane potential – is considered a powerful method for deciphering how brain cells function and interact.

However, current monitoring methods fall short, said the study’s first author Evan W. Miller, a post-doctoral researcher in the lab of Roger Tsien, PhD, Howard Hughes Medical Institute investigator, UC San Diego professor of pharmacology, chemistry and biochemistry and 2008 Nobel Prize co-winner in chemistry for his work on green fluorescent protein.

“The most common method right now monitors the movement of calcium ions into the cell,” said Miller. “It provides some broad indication, but it’s an indirect measurement that misses activity we see when directly measuring voltage changes.”

The new method employs dyes that penetrate only the membrane of neurons, either in in vitro cells cultured with the dye or, for this study, taken up by neurons in a living leech model. When the dyed cells are exposed to light, neuronal firing causes the dye momentarily to glow more brightly, a flash that can be captured with a high-speed camera.

“One of the tradeoffs with using voltage-sensing dyes in the past is that when they were reasonably sensitive to voltage changes, they were slow compared to the actual physiological events,” said Miller. “The new dye gives big signals but is much faster and doesn’t perturb the neurons. We essentially see no lag time between the optical signal and electrodes (used to double-check neuronal activity).”

The new method provides a wider view of neuronal activity, said Miller. More importantly, it makes it possible for neuroscientists to do accurate, single trial experiments. “Right now, you have to repeat experiments with cells, and then average the results, which is physiologically less relevant and meaningful.”

For Tsien, the new dyes address a career-long challenge.

“These results are the first demonstration of a new mechanism to sense membrane voltage, which is particularly satisfying to me because this was the first problem I started working on as a graduate student in 1972, with little success back then,” said Tsien. “Later, we devised indirect solutions such as calcium imaging or dyes that gave big but slow responses to voltage. These techniques have been very useful in other areas of biology or in drug screening, but didn’t properly solve the original problem. I think we are finally on the right track, four decades later.”

Source: University of California, San Diego

Economic Activity Improved In December

February 4th, 2012 Posted in Activity Tags:

Yesterdays news that the Chicago Fed National Activity Index (CFNAI) increased last month provides another data point to consider in the debate about recession risk. Looking backward doesnt necessarily tell us whats coming, but its clear that Decembers economic momentum strengthened. January and beyond, of course, are still open to interpretation.

Led by improvements in production- and employment-related indicators, the Chicago Fed National Activity Index increased to +0.17 in December from 0.46 in November, according to an accompanying statement. The indexs three-month moving average, CFNAI-MA3, increased from 0.19 in November to 0.08 in Decemberits highest value since March 2011.

CFNAI is a weighted average of 85 indicators of US economic activity. The Chicago Fed recommends reading its 3-month moving average (CFNAI-MA3) as follows: a value below -0.70 after a period of economic expansion indicates an increasing likelihood that a recession has begun. By that standard, the December CFNAI-MA3 reading of -0.08 suggests that another downturn was nowhere in sight last month.

Thats no assurance that the coming months wont deteriorate. There are, as if we needed reminding, plenty of risk scenarios out there that might derail the still-fragile recovery. As I keep mentioning, the weak personal income and spending numbers are high on my list of potential trouble spots. Perhaps well learn if this worry is relevant or not when the January update arrives next Friday (Feb. 3).

Theres also Europe to consider and the potential for economic blowback as the Continent struggles to keep its own recession risk at bay. The UK, meantime, has its own problems as it moves closer to a second recession as economy shrinks 0.2%.

Lets not forget that the festering troubles with Iran may wreak havoc on the global economy. With the European Union set to impose economic sanctions on Iran for its nuclear program, the Iranian parliament is threatening to halt oil exports to Europe. Theres no sign of panic in oil trading, at least not yet. But if this crisis rolls on, the possibility for substantially higher energy prices cant be ruled out.

Perhaps the economic outlook isnt as rosy as it appears by looking solely at the data in the rear view mirror. It wouldnt be the first time that focusing on recent history blinds us to whats coming. The problem, of course, is that modeling the future is challenging, to say the least.

If the US does slip into a new recession sometime in the near term because of an exogenous shock from Europe, Iran, or some unknown unknown, does that count as a win for the recession forecasters? We all know that theres always another recession lurking in the future. The timing and specific catalyst are usually the great mysteries. As such, should there be a time limit on recession forecasts?

Church’s new Christian Life Center is a hub of activity

February 1st, 2012 Posted in Activity Tags:

It didnt take long for Canyon Lake United Methodist Churchs
new Christian Life Center to turn into the hub of activity church
officials hoped it would become.

We knew if we built it, people would come, said Richard
Wahlstrom, a longtime church member and the chair of the churchs
project steering committee.

The center, which opened a year and a half ago, is part of an
ongoing bundle of projects the church plans to raise money for this
year, said the Rev. Eric Grinager.

A capital campaign to raise $1.4 million started this month and
will conclude in February.

The first priority on the list is paying off the debt for the
building, which includes three classrooms, a kitchen, bathrooms and
a large multi-purpose room that serves as a dining room and gym,
and can seat 220 people for weddings, award ceremonies and other
activities.

That includes the first floor, Grinager said. It has provided
the church with more classroom space and the luxury of having all
main activities on one floor. Before construction, the dining room
and the kitchen were in the basement.

But that was just phase one of the plan, he added.

The second floor of the building, which is not completed, is
also on the list of projects. The second floor, constructed above
the first-floor kitchen and classrooms, will offer another 2,500
square feet for classrooms.

The church also hopes to update the current church facility,
which was built in the 1950s, and construct a new driveway.

The driveway will come up from Canyon Lake Drive about 100 yards
east of the current driveway, Grinager said. It would be
constructed on the current hill and come directly to the
building.

Church officials hope to finish the projects during the next
three years, but none of the work will begin until the debt is paid
off, Grinager said.

Pay the debt – thats our first goal, he said. Then well
finish the other projects.

If the church is not able to raise the money in three years, it
would have to re-evaluate the projects, Wahlstrom said.

Theyre all important and thats why we hope we meet our goals,
because then we could do them all, he said.

In the meantime, the heart of the Christian Life Center is up
and running, attracting church members and community groups.

It wasnt that way at first, Grinager said.

Part of the challenge was that it was on a pay-as-you-go
basis, he said. The church opened the center, but the kitchen
supplies were not purchased for another nine months.

Thats when the building really started getting used, he
said.

Since then, the church has held its weekly Sunday school classes
and Wednesday night meals and activities there. It also has hosted
wedding receptions, blood drives, mission events and meetings.

Were using it in ways that were never imaginable before
construction, Wahlstrom said.

Its been a great community outreach, Grinager said.

The nearby Montessori school uses the multipurpose room for its
gym classes on Tuesdays, Stevens High School used the room for an
end-of-the-year banquet and several local organizations have used
the building for events and meetings.

He expects to see even more use during the next three years as
the church continues to move on its list of projects.

Its going to facilitate opportunities to serve our neighbors,
he said. We will have more flexibility to offer more things to our
congregation, but also beyond that.

Autism signs ‘can be detected in 6-month-old babies’ by measuring brain activity

January 31st, 2012 Posted in Activity Tags:

Scientists have detected signs of autism in babies as young as six months, leading to hopes of a test for the disorder.

They made the breakthrough by measuring brain activity and believe it could lead to identifying those infants most at risk at a much earlier stage.

Around one in 100 children develops the disorder but symptoms do not usually become apparent until the second year of life.

Brain Activity: the weird world of David Shrigley

January 29th, 2012 Posted in Activity Tags:

What the Hell Are You Doing? The Essential David Shrigley, a compendium of his
drawings published in 2010, has sold more than 20,000 copies. In 2003 he
animated the music video for Good Song by Blur. Between 2005 and 2009 he
produced a weekly cartoon for The Guardian; more recently he was the
political cartoonist for the New Statesman.

You can buy Shrigley T-shirts, badges, guitar plectrums, duvet covers and
greetings cards (though it is hard to imagine sending one without causing
offence). Next month, a retrospective, David Shrigley: Brain Activity, opens
at the Hayward Gallery in London. The organisers are expecting substantial
crowds.

The intriguing thing about Shrigleys work, though, is that unlike much
popular art, it is rarely easy on the eye. His reputation rests upon a
corpus of more than 7,000 works on paper: deranged, abortive little drawings
often accompanied by wobbly text full of spelling mistakes and
crossings-out. Crude, scratchy and instantly recognisable, they appear
animated by ferocious mental distress, like the outpourings of a madman with
no formal art training whatsoever. (In reality, Shrigley graduated from
Glasgow School of Art in 1991.)

Shrigleys pictorial world is a strange, benighted realm. Death and despair
loom large. Decapitated heads, swords, flies, ants and mangy, misshapen
creatures defying every known biological category are recurrent motifs. The
atmosphere is supremely nightmarish, nihilistic and bleak. The novelist Will
Self once compared Shrigleys drawings to the scribblings of a serial killer.

Why then is he so popular? The answer is simple: because he is an exuberantly
gifted humorist. His message may be pessimistic, harping on about the
pointless absurdity of existence, but the manner in which he conveys it is
gloriously funny; there is always laughter in the darkness. As Shrigley puts
it, If you start talking about death, mayhem and misery and it isnt funny,
then it would be quite a hard pill to swallow.

Judging by his drawings, it would be unsurprising to discover that Shrigley,
43, lives in a hovel down some alleyway in the back of beyond. The reality
is somewhat different.

It is a sharp December morning when I arrive at his 19th-century flat in
Glasgows well-to-do West End (he has lived in the city since he was a
student). His wife, Kim, lets me in, because he is still showering after a
morning session of yoga.

When Shrigley, who is 6ft 5in tall, comes downstairs, he is clean-shaven and
dressed in a cosy cable-knit sweater. He wears sandals over white socks,
like a right-on Christian preacher an impression reinforced by his soft
voice and meek manner. There is no flicker of the anarchy I assume must lurk
within.

Im just an actor, he jokes, pointing to the ceiling of his sitting-room.
Theres a dribbling, paranoid wreck who lives up there. He pours us both a
coffee. I dont think Im clinically depressed, he continues with a wry
smile. So I dont know where the darkness comes from.

Born in Macclesfield in 1968, Shrigley grew up in a redbrick suburb of
Leicester after his family moved there in 1970. His father was an
electronics engineer, his mother a computer programmer. Both were practising
Christians.

My dad is a Christian fundamentalist, Shrigley says. He didnt get into it
until I was a teenager, but it really freaked me out. During his teens
Shrigley decided he no longer wanted to go to church. There are so many
contradictions within Christianity. Why is the Church so interested in the
congregations sexual behaviour? Why do they give homosexuals a hard time?
There are a number of things that I have never been able to reconcile with
organised religion.

Despite this, he is reluctant to call himself an atheist. Im definitely not
a practising Christian, he says. But I have sympathy with religious
belief. People who need to disprove that there is a spiritual life somehow
it spoils the magic of being alive. Richard Dawkins is like an annoying
sixth-former saying, Yes, but I think youll findhellip; All right, Richard,
whatever. You win. There is no God. Religion is bad. Except I dont think
that religion is necessarily a negative thing. I think that humanity is
endemically predisposed to do bad things, and religion is sometimes used to
justify those bad things. Ultimately, though, religion is a positive thing.
There are other forces in the world that arent positive like capitalism.

Interviewers often emphasise Shrigleys religious upbringing, as though it
offers a key to unlock the meaning of his work. Shrigley, though, is less
sure that it had such a strong impact on his imagination.

It wasnt some crazy Oranges Are Not the Only Fruit-type scenario where I was
brutalised by my parents, he says. There were things we werent supposed
to do when I was a little kid like I wasnt allowed violent comic books.
Obviously, though, I was obsessed with violence and death and mayhem. I was
really keen on making torture chambers and places of execution for Action
Man out of cardboard boxes from Tesco. Its just what little boys do, isnt
it?

Shrigley also spent a lot of time drawing. I was the kid who could draw
dinosaurs better than anyone else in my class, he says. Even when I was
four years old, I was making peculiar little drawings with speech bubbles.
In a sense, Ive been doing the same thing my entire life.

After completing his art and design foundation year at Leicester Polytechnic,
he enrolled on the influential environmental art course at Glasgow School of
Art in 1988. Angry with his teachers after he was awarded a 2:2 in finals,
though, he decided that he no longer wanted to become an artist. I was
always being given a hard time for making art that was a bit stupid and
funny, so I decided to become a cartoonist even though I had no
interest in cartoons or comic books.

To catch the eye of prospective editors, he carefully reworked his initially
scruffy sketches to imitate a professional finish. He did sell one
cartoon, to Punch but it wasnt printed before the magazine closed in
1992. At the suggestion of the conceptual artist Jonathan Monk, his friend
and former flatmate, Shrigley reconsidered becoming an artist, and began
presenting his drawings as they first appeared, instead of polishing them
up.

In 1994 he produced a book called Blanket of Filth which were just the
drawings as they came out. He made about 100 copies, which he sold to
people at art openings or in the pub. From that point on, I was making a
book every few months. In the years that followed, he didnt feel any
urgency about his career. He was content to be known as the guy who made
these interesting, funny, oblique drawings.

The breakthrough came in 1995, when his work was featured in and on the cover
of the art magazine Frieze. It was like going from being nobody to somebody
in the art world overnight, he says. Suddenly you are stamped official
artist. Before long he was offered solo exhibitions in Britain and across
Europe. I remember feeling slightly guilty because I hadnt worked as hard
as everybody else. It wasnt my intention to become the kind of artist who
would be on the cover of Frieze.

Shrigley may have started out as a slacker, but over the past decade and a
half he has fashioned a sustained career for himself as a successful fine
artist. Both the Tate and the Museum of Modern Art in New York now own
examples of his work. The new exhibition at the Hayward Gallery will
demonstrate the extent of his oeuvre. As well as paintings and drawings, it
will feature several deadpan sculptures, including a stuffed Jack Russell
holding a placard that states, Im dead (a Surrealistic joke that would
surely have pleased Magritte). There will also be a selection of
photographs, and some short animated films such as Sleep (2008), a burlesque
of Andy Warhols 1963 experimental film of the same name, and Light Switch
(2007), which alludes to the Turner Prize-winning work of the conceptual
artist Martin Creed.

Does Shrigley hope that the Hayward exhibition will remind his audience that
he is a proper artist as well as a cartoonist? I dont mind how people
perceive me. I am very resistant to being defined as an illustrator, but I
am a cartoonist of sorts. I call myself an artist because the term
encompasses everything I do. Also I make a living as a fine artist, I dont
make a living as a cartoonist.

Shrigley does not sell work for as much as some of his contemporaries (from
what he tells me, I get the impression that his own prices have yet to reach
tens of thousands of pounds). At the core of what I do are drawings, and
because there are so many of them, they only acquire a certain price, he
explains. I drive a Honda, put it that way. But I have nothing to complain
about. We have a very nice flat, and Kim doesnt have to have a job.

Sitting serenely on his sofa, a neatly folded green mohair rug beside him,
Shrigley seems pleased with his comfortable existence. Most days, he works
for eight hours in one of his two studios making sculptures or drawings (he
discards three out of every four of the latter). He and Kim, a former
graphic designer whom he met in the late 1990s and married in 2010, are
thinking about moving to Brighton: Ive always loved the sea. He seems
relaxed about the fact that they are unlikely to have children. Were
getting a bit old for it. Were going to get a dog. Were thinking
about a miniature schnauzer. All my friends have kids, but if you want to be
really environmentally friendly, dont have any.

It is easy to be charmed by Shrigleys gentleness, as well as his witty line
in self-deprecation easy, in fact, to forget that he has published almost 30
madcap books with titles such as Ants Have Sex in Your Beer and Kill Your
Pets (I worry for his future miniature schnauzer). Even Pass the Spoon, the
sort-of opera that Shrigley wrote last year with the Irish composer David
Fennessy, has a sinister quality. Like a deranged version of the BBCs
cooking competition MasterChef, the production, which ran at Glasgows
Tramway Theatre in November, features two celebrity chefs, a cast of singing
vegetables that eventually get chopped up, and a banana hell-bent on
escaping its fate of becoming banana custard. (It will have its London
premiere at the Queen Elizabeth Hall in May.)

Does Shrigley concede that his work is dark? I am aware that theres quite a
mordant world view, he says. Sometimes I feel the work is a bit
relentlessly dark and nasty, and I try to pull back a little, but Im not
really in control of the content it just comes out in a very intuitive
fashion. Being an artist gives you a voice and that voice is cathartic.
Youre purging yourself. He smiles. Im a pretty happy, well-balanced
person, really.

But if he is so happy, then isnt his unruly vision inauthentic? Isnt he
cheating his audience? After all, he draws like a sociopathic amateur, but
operates as a balanced professional. His work has the stamp of outsider art,
yet hes an art-world insider friends, for instance, with Richard Wright
and Martin Boyce, who have both won the Turner Prize. For the first time,
Shrigley slightly bristles. You say all these things and, to be honest, I
dont care. My work is not autobiography, thats for sure. But that doesnt
mean its not authentic. Graphically, theres no artifice. All the mistakes
I make are real mistakes. I never draw anything twice. Im not interested in
making aesthetic, beautiful drawings.

He draws breath. Look, Im not a lunatic, whereas the voice in my work is
pretty lunatic, Ill readily admit that. But I want it to be because you
cant be a lunatic in real life. Whats the alternative? Does anybody make
happy art? He sips his coffee. Maybe there is something endemic within
humour that has to be cruel in some way. But at least my work is funny. I do
laugh at my own work. It does amuse me. That means its sort of happy.

David Shrigley: Brain Activity is at the Hayward Gallery, London, from
February 1 to May 13 (southbankcentre.co.uk)